Development Status and trend of HPV vaccine

Abstract

Cervical cancer causes significant morbidity and mortality world widely, and human papilloma virus is the major factor that causes cervical cancer incidence. The carcinogenic proteins of HPV can induce malignant metastasis of cervical squamous epithelial cells. There are currently two human papilloma virus prophylactic vaccines listed, but the protection offered by current vaccines is primarily against HPV types used to derive the vaccine. So we review the status and progress of the HPV vaccine in recent years, and the potential clinical application of the vaccine.