Research progress in detection of rotavirus

Abstract

RVs causes significant morbidity and mortality world widely, they are the main etiologic agents of serious diarrheal disease and the major cause of gastroenteritis in infants and young children under 5 year of age. Because there is no specific treatment for RV infections, rotavirus vaccines were considered to be the most effective way to prevent rotavirus infections. Thus, a rapid, specific and sensitive detection method is of the utmost importance for diagnosing and monitoring of rotaviruses, and also for evaluating of rotavirus vaccines. In this report, we reviewed the process of the detection methods for rotaviruses in recent years, intending to provide useful information for developing a rapid, effective and robust assay for rotaviruses and rotavirus vaccines.